4E 0 — End of the Oblivion Crisis
The banishing of Mehrunes Dagon from Tamriel by the Champion of Cyrodiil, Martin Septim, and the avatar of Akatosh ends the Oblivion Crisis. The Septim bloodline ends and the Amulet of Kings is destroyed. The Third Era ends, marking the beginning of the Fourth.
The Fourth Era begins with no Emperor on the throne of Tamriel. High Chancellor Ocato, the Elder Council, and the Blades try to maintain order. The provinces start to take advantage of the Empire's weakened state.

4E ?? — Red Mountain erupts; Vvardenfell is destroyed.
In Vivec's absence, the Ministry of Truth becomes unstable. Vuhon creates an Ingenium that uses at first dozens of dying souls, then a small number of living ones to stabilize the rock. The soul of Sul's wife Ilzheven was among them. In a fight to free her, the Ingenium is destroyed and the rock crashes into the city of Vivec with all the energy it originally had. The impact causes Red Mountain to erupt and destroys the entire island of Vvardenfell, as well as causing massive destruction to the rest of the province.

4E ?? — The Empire Collapses
Black Marsh secedes from the Empire; it is soon followed by Elsweyr.
The Thalmor seize control of the old Aldmeri Dominion (Valenwood and the Summerset Isle).
The Argonians invade and conquer Morrowind after the eruption of Red Mountain.

4E ?? — Titus Mede is crowned the new emperor by conquest.

4E 18 — Prince Attrebus Mede is born.

4E 23 — Annaïg Hoïnart is born.

4E 40s — Umbriel, a floating city, appears on the coast of Black Marsh, heading toward Morrowind.
The city of Lilmoth, Black Marsh, the home of Annaïg, is destroyed in the process.

Third Century

4E 201 — The High King of Skyrim is assassinated by Ulfric Stormcloak at Solitude.

4E 201 — The Nords of Skyrim engage in a civil war.

Imperial General Tullius is charged with crushing the Stormcloak rebellion.